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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B1
All Species:
31.21
Human Site:
S49
Identified Species:
57.22
UniProt:
O75533
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75533
NP_036565.2
1304
145830
S49
E
I
Y
G
G
S
D
S
R
F
A
G
Y
V
T
Chimpanzee
Pan troglodytes
XP_516006
1379
153963
S124
E
I
Y
G
G
S
D
S
R
F
A
G
Y
V
T
Rhesus Macaque
Macaca mulatta
XP_001086317
1397
156322
S142
E
I
Y
G
G
S
D
S
R
F
A
G
Y
V
T
Dog
Lupus familis
XP_857149
1312
146628
S49
E
I
Y
G
G
S
D
S
R
F
A
G
Y
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99NB9
1304
145798
S49
E
I
Y
G
G
S
D
S
R
F
A
G
Y
V
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421912
1383
154834
S131
E
I
Y
G
G
S
D
S
R
F
A
G
Y
V
T
Frog
Xenopus laevis
O57683
1307
146196
S49
E
I
Y
G
G
S
D
S
R
F
T
G
Y
V
T
Zebra Danio
Brachydanio rerio
XP_684311
1315
147162
S52
E
I
Y
G
G
S
D
S
R
F
D
G
Y
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623732
1315
147662
N53
D
I
Y
D
G
S
N
N
K
Y
E
G
Y
V
T
Nematode Worm
Caenorhab. elegans
NP_497853
1322
147305
V54
D
T
D
V
Y
G
S
V
R
G
E
N
R
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323970
1267
141858
R37
D
L
Y
G
G
V
D
R
N
A
Y
E
T
S
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_201232
1269
141432
G36
T
F
D
R
D
L
Y
G
G
N
D
R
A
S
Y
Baker's Yeast
Sacchar. cerevisiae
P49955
971
110009
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
93.3
99.3
N.A.
99.9
N.A.
N.A.
N.A.
93.7
96.6
93.7
N.A.
N.A.
82.4
65.1
N.A.
Protein Similarity:
100
94.5
93.3
99.3
N.A.
100
N.A.
N.A.
N.A.
93.7
98.3
96.4
N.A.
N.A.
88.9
76.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
93.3
86.6
N.A.
N.A.
53.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
93.3
93.3
N.A.
N.A.
86.6
20
N.A.
Percent
Protein Identity:
68.4
N.A.
N.A.
68.3
40.4
N.A.
Protein Similarity:
79.3
N.A.
N.A.
79.1
53.1
N.A.
P-Site Identity:
26.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
47
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
16
8
8
0
70
0
0
0
16
0
0
8
0
% D
% Glu:
62
0
0
0
0
0
0
0
0
0
16
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
62
0
0
0
0
0
% F
% Gly:
0
0
0
70
77
8
0
8
8
8
0
70
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
8
8
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
70
0
0
8
8
0
0
% R
% Ser:
0
0
0
0
0
70
8
62
0
0
0
0
0
16
8
% S
% Thr:
8
8
0
0
0
0
0
0
0
0
8
0
8
0
70
% T
% Val:
0
0
0
8
0
8
0
8
0
0
0
0
0
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
77
0
8
0
8
0
0
8
8
0
70
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _